Journal of Liver Cancer

Hong Seok Jang

3 Articles

A Case of Advanced Hepatocellular Carcinoma in Twenties Treated by Multimodality Therapy: Jang Eun Lee, Na Ri Yoon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Dong Goo Kim, Ho Jong Chun, Byung Gil Choi, Hae Giu Lee, Hong Seok Jang, Chan Kwon Jung, Eun Sun Jang; Journal of the Korean Liver Cancer Study Group. 2009;9(1):82-85. Published online June 30, 2009

Abstract PDF: The prognosis of young patients with hepatocellular carcinoma is remains controversial. Here we report a case of advanced hepatocellular carcinoma in twenty, successfully treated with transarterial chemolipidolization (TACL), systemic chemotherapy, radiation therapy and surgical resection. Previously healthy 28 years old woman was admitted for treatment of hepatocellular carcinoma. Abdominal CT showed a diffuse infiltrative HCC involving both lobes with intrahepatic bile duct invasion and pericardial lymphadenopathy. She was treated TAC with systemic chemotherapy and external beam radiotherapy. 6 months after these treatments, main tumor and the pericardial lymph node were decreased in size. And then extended left lobectomy and systemic chemotherapy were done. The pericardial lymph node was markedly decreased. The patient has been followed for 10 months without evidence of regional tumor recurrence.

A Case of the Complete Remission of a Solitary Extrahepatic Bile Duct Hepatocellular Carcinoma without Primary Hepatic Parenchymal Lesions by Cyberknife Treatment: Soung Won Jeong, Si Hyun Bae, Hyun Young Woo, Chan Ran You, Won Hang Hur, Jong Young Choi, Seung Kew Yoon, Dong Hoon Lee, Young Jun Lee, Jae Young Byun, Hong Seok Jang; Journal of the Korean Liver Cancer Study Group. 2008;8(1):92-97. Published online June 30, 2008

Abstract PDF: A 69-year-old man patient was hospitalized by confused mentality. He had chronic hepatitis B virus infection and was diagnosed with liver cirrhosis 20 years ago. Abdominal CT showed about 2×1 cm sized polypoid mass with mild arterial enhancement at the S4 of liver, causing moderate dilatation of the left IHBD. In the CTHA-AP, intraductal mass was hyperattenuated at arterial phase and washed out at portal phase. Celiac angiography revealed nodular tumor staining correlating to intraductal mass on CT. In MRCP and ERCP, a polypoid lesion was noted at the orifice of left main intrahepatic duct. The patient was treated with cyber-knife for 3 days with 3600 cGy. In follow up CT after 2 month of cyber-knife treatment, there was regression of previously noted left IHBD dilatation and no definite enhancing intraductal mass.

A Case of Cyberknife Treatment for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: Chan Ran You, Si Hyun Bae, Hyun Young Woo, Soung Won Jeong, Jong Young Choi, Seung Kew Yoon, Hong Seok Jang, Dong Hoon Lee, Byung Gil Choi; Journal of the Korean Liver Cancer Study Group. 2007;7(1):82-86. Published online June 30, 2007

Abstract PDF: A 64 year-old-male patient was transferred to our hospital for infiltrative hepatocellular carcinoma (HCC) without treatment response because of treatment failure and disease progression. He had been diagnosed infiltrating HCC 9 months ago and then treated with three times of transarterial chemolipiodolization (TACL) in other hospital. But, HCC was progressed. Abdominal CT showed infiltrating HCC in S7 and a small daughter nodule in S8 with right and main portal vein tumor thrombosis (PVTT). We performed stereotatic radiosurgery (Cyberknife) for the treatment of PVTT and four times of TACL for the treatment of intrahepatic HCC every 4weeks. The total radiation doses using with Cyberknife were 36Gy with a prescription isodose 80% in 3 fractions over the three consecutive days. After treatment, infiltrating HCC was decreased in size and PVTT was markedly regressed. Response rate of serum AFP was 57.2%. In conclusion, we report the case of good treatment response in the patient with HCC with PVTT after combination treatment of Cyberknife and TACL.